Alpha-2a adrenergic receptor (α2AR) activation in genetic absence epilepsy: An absence status model?
Melis YavuzSerdar AkkolFiliz OnatPublished in: Epilepsia open (2023)
This study presents an absence status epilepticus animal model that is activated by α2AR activation to investigate the pathophysiological role of absence status. Unlike other agents ATI switched off the second set of absence statuses to normal SWDs, without sedation or lethargy, can show it may preferentially block absence status-like activity.