Intra-tumor heterogeneity in breast cancer has limited impact on transcriptomic-based molecular profiling.

Govindasamy-Muralidharan KarthikMattias RantalainenGustav StålhammarJohn LövrotIkram UllahAmjad AlkodsiRan MaLena WedlundJohan LindbergJan FrisellJonas BerghJohan Hartman

Published in: BMC cancer (2017)

Our results suggest that macroscopic intra-tumoral transcriptomic heterogeneity is limited and unlikely to have an impact on molecular diagnostics for most patients.

Keyphrases

single cell
rna seq
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors