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Intron retention enhances gene regulatory complexity in vertebrates.

Ulf SchmitzNatalia PinelloFangzhi JiaSultan AlasmariWilliam RitchieMaria-Cristina KeightleyShaniko ShiniGraham J LieschkeJustin J-L WongJohn E J Rasko
Published in: Genome biology (2017)
Our study provides unique insights concerning the role of IR as a robust and evolutionarily conserved mechanism of gene expression regulation. Our findings enhance our understanding of gene regulatory complexity by adding another contributor to evolutionary adaptation.
Keyphrases
  • gene expression
  • dna methylation
  • genome wide