Identification of pan-cancer/testis genes and validation of therapeutic targeting in triple-negative breast cancer: Lin28a-based and Siglece-based vaccination induces antitumor immunity and inhibits metastasis.
Jason A CarterBharati MattaJenna BattagliaCarter SomervilleBenjamin D HarrisMargaret LaPanGurinder S AtwalBetsy J BarnesPublished in: Journal for immunotherapy of cancer (2023)
Our results present a novel strategy for the identification of highly immunogenic CTAs for the development of targeted vaccines that induce antitumor immunity and inhibit metastasis.