The frequencies of CYP2D6 alleles and their impact on clinical outcomes of adjuvant tamoxifen therapy in Syrian breast cancer patients.

Wouroud Ismail Al-Khalil Lana Al-Salhi Sara Rijjal Majd Aljamali Lama A Youssef

Published in: BMC cancer (2022)

Our findings show no association between CYP2D6 phenotype and treatment outcomes of tamoxifen in Syrian breast cancer patients. Nevertheless, a worse DFS was revealed in patients with 1847A/A genotype (*4/*4).

Keyphrases

breast cancer cells
estrogen receptor
positive breast cancer
early stage
single cell
bone marrow
cell therapy
replacement therapy