Involvement of EP2 and EP4 Receptors in Eosinophilic Esophagitis: A Pilot Study.
Franziska DurchscheinAndreas EhererMagdalena GrillEva M SturmVeronika PommerCord LangnerChristoph HögenauerRudolf SchichoPublished in: Digestive diseases and sciences (2019)
Activation of EP2 and EP4 receptors may inhibit eosinophil recruitment to the esophageal mucosa. However, their activation could negatively affect esophageal barrier integrity suggesting that eosinophilic rather than epithelial EP2 and EP4 have a protective role in EoE.
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