A novel fusion gene involving PDGFRB and GCC2 in a chronic eosinophilic leukemia patient harboring t(2;5)(q37;q31).

Noriyoshi IriyamaHiromichi TakahashiHiromu NaruseKatsuhiro MiuraYoshihito UchinoMasaru NakagawaKazuhide IizukaTakashi HamadaYoshihiro HattaTomohiro NakayamaMasami Takei

Published in: Molecular genetics & genomic medicine (2019)

This is the first case report demonstrating the GCC2 gene as a partner of PDGFRB in the pathogenesis of CEL.

Keyphrases

case report
copy number
genome wide
genome wide identification
acute myeloid leukemia
bone marrow
gene expression
dna methylation
genome wide analysis
transcription factor
hiv infected
hepatitis c virus
drug induced