Circulating Folate and Folic Acid Concentrations: Associations With Colorectal Cancer Recurrence and Survival.
Anne J M R GeijsenArve UlvikBiljana GigicDieuwertje E G KokFranzel J B van DuijnhovenAndreana N HolowatyjStefanie BrezinaEline H van RoekelAndreas BaierlMichael M BergmannJürgen BöhmMartijn J L BoursHermann BrennerStéphanie O BreukinkMary P BronnerJenny Chang-ClaudeJohannes H W de WiltWilliam M GradyThomas GrünbergerTanja GumpenbergerEsther HerpelMichael HoffmeisterLyen C HuangJolanta D JedrzkiewiczEric T P KeulenRama KiblawiTorsten KölschJanna Lena KooleKatharina KosmaEwout A KouwenhovenFlip M KruytGry KvalheimChristopher I LiTengda LinJennifer OseT Bartley PickronCourtney L ScaifePeter SchirmacherMartin A SchneiderPetra Schrotz-KingMarie C SingerEric R SwansonPeter van DuijvendijkHenk K van HalterenMoniek van ZutphenKathy VickersF Jeroen VogelaarEvertine WesselinkNina HabermannAlexis B UlrichPer M UelandMatty P WeijenbergAndrea GsurCornelia M UlrichEllen KampmanPublished in: JNCI cancer spectrum (2020)
Circulating folate and folate catabolite concentrations at colorectal cancer diagnosis were not associated with recurrence and survival. However, caution is warranted for high blood concentrations of folic acid because they may increase the risk of colorectal cancer recurrence.
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