Comparison of von Willebrand factor platelet-binding activity assays: ELISA overreads type 2B with loss of HMW multimers.

Attila SzederjesiLuciano BaroncianiUlrich BuddeGiancarlo CastamanPaola ColpaniAndrew S LawrieYuan LiuRobert MontgomeryFlora PeyvandiReinhard SchneppenheimJürgen PatzkeImre Bodó

Published in: Journal of thrombosis and haemostasis : JTH (2020)

Different assay principles may lead to discrepant results for certain VWD types or mutations. Therefore, a more extensive study for a large number of patients is needed to better characterize the incidence and relevance of such assay-specific differences.

Keyphrases

high throughput
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
patient reported outcomes
transcription factor
dna binding