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Association of 5-aminolevulinic acid fluorescence guided resection with photodynamic therapy in recurrent glioblastoma: a matched cohort study.

Erasmo Barros da Silva JuniorMarília Wellichan Mancini VasquezBernardo Correa de Almeida TeixeiraMaurício Coelho NetoFlávia SprengerJorge Luis Novak FilhoLuciana Almeida-LopesRicardo Ramina
Published in: Acta neurochirurgica (2024)
The association of PDT immediately after 5-ALA FGR for recurrent malignant glioma seems to be associated with better survival without additional or severe morbidity. Despite the need for larger, randomized series, the proposed treatment is a feasible and safe addition to the reoperation.
Keyphrases
  • photodynamic therapy
  • fluorescence imaging
  • open label
  • early onset
  • placebo controlled