Lifetime Exposure to Cigarette Smoke, B Cell Tumor Immune Infiltration, and Immunoglobulin Abundance in Ovarian Tumors.

Cassandra A Hathaway Mary K Townsend Tianyi Wang Christine Vinci Danielle E Jake-Schoffman Jonathan L Hecht Daryoush Saeed-Vafa Carlos Moran Segura Jonathan V Nguyen José R Conejo-Garcia Brooke L Fridley Shelley T Tworoger

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2024)

IgA has been associated with improved ovarian cancer outcomes, suggesting that although smoking is associated with poor outcomes in ovarian cancer patients, it may lead to improved tumor immunogenicity.

Keyphrases

smoking cessation
metabolic syndrome
adipose tissue
antibiotic resistance genes
insulin resistance
microbial community