Safety and efficacy of single cycle induction treatment with cisplatin/docetaxel/ durvalumab/tremelimumab in locally advanced HNSCC: first results of CheckRad-CD8.

Markus HechtAntoniu Oreste GostianMarkus EcksteinSandra RutznerJens von der GrünThomas IllmerMatthias G HautmannGunther KlautkeSimon LabanThomas BrunnerAxel HinkeIna BeckerBenjamin FreySabine SemrauCarol I GeppertArndt HartmannPanagiotis BalermpasWilfried BudachUdo S GaiplHeinrich IroRainer Fietkau

Published in: Journal for immunotherapy of cancer (2021)

Single cycle induction treatment with cisplatin/docetaxel and durvalumab/tremelimumab is feasible and achieves a high biopsy-proven pCR rate.

Keyphrases

locally advanced
squamous cell carcinoma
rectal cancer
neoadjuvant chemotherapy
lymph node
replacement therapy
phase ii study