Tweaking EMT and MDR dynamics to constrain triple-negative breast cancer invasiveness by EGFR and Wnt/β-catenin signaling regulation.
Rajib ShomeSiddhartha Sankar GhoshPublished in: Cellular oncology (Dordrecht) (2021)
Our data indicate that the synergistic action of targeting both the EGFR and Wnt/β-catenin signaling pathways in TNBC cells may open up new avenues for combatting this disease.
Keyphrases
- cell proliferation
- small cell lung cancer
- epithelial mesenchymal transition
- induced apoptosis
- epidermal growth factor receptor
- signaling pathway
- tyrosine kinase
- stem cells
- cell cycle arrest
- cancer therapy
- pi k akt
- minimally invasive
- multidrug resistant
- electronic health record
- endoplasmic reticulum stress
- big data
- oxidative stress
- cell death