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Comparing the efficacy and safety of insulin detemir versus neutral protamine hagedorn insulin in treatment of diabetes during pregnancy: a randomized, controlled study.

Jing JiZhangya HeZhao YangYang MiNa GuoHong ZhaoJiayi GaoZhengfeei MaXiaoqin LuoZhen Han
Published in: BMJ open diabetes research & care (2021)
For the treatment of gestational diabetes, both RRR-IDet plan and RRR-NPH plan were reported to control blood glucose effectively. Compared with NPH, IDet could control blood glucose and reached the targets faster and more effectively, thus reducing the number of insulin injections and the incidence of hypoglycemia in pregnant women without increasing adverse birth outcomes. Therefore, for pregnant women with gestational diabetes, who require insulin therapy, IDet would be an ideal basal insulin being worthy of promotion in clinical settings.
Keyphrases
  • glycemic control
  • blood glucose
  • type diabetes
  • pregnant women
  • weight loss
  • insulin resistance
  • cardiovascular disease
  • blood pressure
  • risk factors
  • skeletal muscle
  • gestational age
  • ultrasound guided
  • platelet rich plasma