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Two Germline Pathogenic Variants in Cancer Susceptibility Genes and Their Null Implication in Breast Cancer Pathogenesis: The Importance of Tumoral Homologous Recombination Deficiency Testing.

Alejandra RezqallahSara Torres-EsquiusAlba Llop-GuevaraMara CruellasMaría Teresa Martínez MartínezMarcel RomeyCarsten DenkertVioleta SerraIsabel ChirivellaJudith Balmaña
Published in: JCO precision oncology (2024)
Homologous recombination proficiency in patients with breast cancer despite germline PALB2/RAD51C pathogenic variants.
Keyphrases
  • dna repair
  • dna damage
  • copy number
  • papillary thyroid
  • genome wide
  • squamous cell
  • childhood cancer
  • oxidative stress
  • squamous cell carcinoma
  • replacement therapy
  • young adults