Methylated SEPTIN9 plasma test for colorectal cancer detection may be applicable to Lynch syndrome.
Megan P HitchinsIngrid P VogelaarKevin BrennanSigurdis HaraldsdottirNianmin ZhouBrock MartinRocio AlvarezXiaopu YuanSungjin KimMaha GuindiAndrew E HendifarMatthew F KaladyJennifer DeVecchioJames M ChurchAlbert de la ChapelleHeather HampelRachel PearlmanMaria ChristensenCarrie SnyderStephen J LanspaRobert W HaileHenry T LynchPublished in: BMJ open gastroenterology (2019)
These preliminary findings suggest mSEPT9 may demonstrate similar diagnostic performance characteristics in LS as in the average-risk population, warranting a well-powered prospective case-control study.