Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies.
Mala PandeAron JoonAbenaa M BrewsterWei V ChenJohn L HopperCathy EngSanjay SheteGraham CaseyFredrick SchumacherYi LinTabitha A HarrisonEmily WhiteHabibul AhsanIrene L AndrulisAlice S WhittemoreIsabelle DurotAung Ko WinEnes MakalicDaniel F SchmidtMiroslaw K KapuscinskiHeather M Ochs-BalcomSteven GallingerMark A JenkinsPolly A NewcombNoralane M LindorUlrike PetersChristopher I AmosPatrick M LynchPublished in: PloS one (2018)
The results of this exploratory analysis did not find clear evidence for a susceptibility locus with a pleiotropic effect on hereditary breast and colorectal cancer risk, although the suggestive association of genetic variation in the region of ROBO1, a potential tumor suppressor gene, merits further investigation.