Biological Agents in the Treatment of Crohn's Disease: A Propensity Score-Matched Analysis From the Prospective Persistence Australian National IBD Cohort (PANIC3) Study.

John David Chetwood Yanna Ko Aviv Pudipeddi Viraj Kariyawasam Sudarshan Paramsothy Rupert W L Leong

Published in: The American journal of gastroenterology (2024)

This large national prospective database with nonhierarchical prescribing of biological agents did not identify superior persistence of any agent in bio-naive CD. However, for patients with bio-experienced CD, persistence was greater with ustekinumab.

Keyphrases

quality improvement
primary care
adverse drug
nk cells
hiv infected
emergency department
combination therapy
replacement therapy