Rare variant analysis of essential tremor-associated genes in early-onset Parkinson's disease.

Dongxiao LiangYuwen ZhaoHongxu PanXun ZhouRuncheng HeXiaoxia ZhouJinxia YangYige WangXiaoting ZhouZhou ZhouQian XuXinxiang YanJinchen LiJi-Feng Guo Bei-Sha Tang Qiying Sun

Published in: Annals of clinical and translational neurology (2020)

This is the first systematic analysis of ET-associated genes in EOPD. The suggestive association between TNEM4 and EOPD provides new evidence for a genetic link between ET and PD.

Keyphrases

early onset
genome wide
late onset
bioinformatics analysis
genome wide identification
dna methylation
deep brain stimulation
copy number
gene expression
transcription factor