Characteristics and risk factors of Functional Dyspepsia fulfilling the Rome IV Criteria overlapping with Gastroesophageal Reflux Disease, Irritable Bowel Syndrome, and Functional Constipation in South China.

FD overlap was quite common in China with high economic burden and poor quality of life, FD patients with history of gastroenteritis, anxiety, depression, and poor sleep quality were more likely to have overlap disorders. Awareness of the physical and psychosocial stressors in overlapping condition would help optimize the management of FD overlap in clinical practice.