A genome-wide association study of susceptibility to upper urinary tract infections.

Helene M FlatbyAnuradha RaviKristin V LiyanarachiJan E AfsetHumaira RasheedBen M BrumptonKristian HveemBjørn O ÅsvoldAndrew T DeWanErik SolligårdJan K DamåsTormod Rogne

Published in: The Journal of infectious diseases (2024)

We found that genetic variants near TSN was associated with the risk of upper UTIs among females. In addition, we found several genetic loci with suggestive associations with the risk of upper UTIs. Finally, MR analyses found smoking to be a potential causal risk factor for upper UTIs.

Keyphrases

genome wide association study
urinary tract infection
genome wide
smoking cessation
copy number
dna methylation