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Molecular Genetics in Neuroblastoma Prognosis.

Margherita LeroneMarzia OgnibeneAnnalisa PezzoloGiuseppe MartuccielloFederico ZaraMartina MoriniKatia Mazzocco
Published in: Children (Basel, Switzerland) (2021)
In recent years, much research has been carried out to identify the biological and genetic characteristics of the neuroblastoma (NB) tumor in order to precisely define the prognostic subgroups for improving treatment stratification. This review will describe the major genetic features and the recent scientific advances, focusing on their impact on diagnosis, prognosis, and therapeutic solutions in NB clinical management.
Keyphrases
  • genome wide
  • copy number
  • dna methylation
  • gene expression
  • single molecule