Safety and efficacy of intraventricular immunovirotherapy with oncolytic HSV-1 for CNS cancers.
Kyung-Don KangJoshua D BernstockStacie K TotschSam E GaryAbbey RoccoLi NanRong LiTina EtminanXiaosi HanElizabeth Ann BeierleTanja EisemannRobert J Wechsler-ReyaSejong BaeRichard J WhitleyG Yancey GillespieJames M MarkertGregory K FriedmanPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Toxicity from intraventricular oHSV can be mitigated resulting in therapeutic benefit. These data support clinical translation of intraventricular G207.