Spectral flow cytometry identifies distinct nonneoplastic plasma extracellular vesicle phenotype in glioblastoma patients.
Abudumijiti Zack AibaidulaCori E FainLuz Cumba GarciaAnnelise WierSamantha M BouchalMegan M BaumanMi-Yeon JungJann N SarkariaAaron J JohnsonIan F ParneyPublished in: Neuro-oncology advances (2023)
Multiparametric analysis demonstrates that GBM patients have a distinct nonneoplastic plasma EV phenotype compared to ND. This simple rapid analysis can be performed without purifying tumor EVs and may serve as the basis of a liquid biopsy.