Alteration of extracellular matrix proteins in atrophic periodontal ligament of hypofunctional rat molars.

Daneeya Na NanVincent EvertsJoao N FerreiraVorapat TrachooThanaphum Osathanon Nuttha KlincumhomPrasit Pavasant

Published in: BDJ open (2023)

Our results revealed that loss of occlusal force disrupts deposition of some major matrix proteins in the PDL, underscoring the relevance of mechanical forces in maintaining periodontal tissue homeostasis by modulating ECM composition.

Keyphrases

extracellular matrix
signaling pathway
oxidative stress
single molecule
single cell