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Microfluidic devices fabricated using fast wafer-scale LED-lithography patterning.

Pavan K ChallaTadas KartanasJerome CharmetTuomas P J Knowles
Published in: Biomicrofluidics (2017)
Current lithography approaches underpinning the fabrication of microfluidic devices rely on UV exposure of photoresists to define microstructures in these materials. Conventionally, this objective is achieved with gas discharge mercury lamps, which are capable of producing high intensity UV radiation. However, these sources are costly, have a comparatively short lifetime, necessitate regular calibration, and require significant time to warm up prior to exposure taking place. To address these limitations we exploit advances in solid state sources in the UV range and describe a fast and robust wafer-scale laboratory exposure system relying entirely on UV-Light emitting diode (UV-LED) illumination. As an illustration of the potential of this system for fast and low-cost microfluidic device production, we demonstrate the microfabrication of a 3D spray-drying microfluidic device and a 3D double junction microdroplet maker device.
Keyphrases
  • low cost
  • high intensity
  • circulating tumor cells
  • high throughput
  • single cell
  • light emitting
  • solid state
  • aqueous solution
  • label free
  • drinking water
  • resistance training
  • body composition
  • carbon dioxide