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Structure alignment-based classification of RNA-binding pockets reveals regional RNA recognition motifs on protein surfaces.

Zhi-Ping LiuShutang LiuRuitang ChenXiaopeng HuangLing-Yun Wu
Published in: BMC bioinformatics (2017)
Large-scale RNA-binding pockets on protein surfaces are grouped by measuring their structural similarities. This similarity network-based framework provides a convenient method for modeling the structural relationships of functional pockets. The local structural patterns identified serve as structure motifs for the recognition with RNA on protein surfaces.
Keyphrases
  • binding protein
  • protein protein
  • biofilm formation
  • machine learning
  • dna binding
  • transcription factor
  • candida albicans