Electrochemical Palladium-Catalyzed Oxidative Carbonylation-Cyclization of Enallenols.
Jianwei ZhangBiswanath DasOscar VerhoJan E BäckvallPublished in: Angewandte Chemie (International ed. in English) (2022)
Herein, we report an electrochemical oxidative palladium-catalyzed carbonylation-carbocyclization of enallenols to afford γ-lactones and spirolactones, which proceeds with excellent chemoselectivity. Interestingly, electrocatalysis was found to have an accelerating effect on the rate of the tandem process, leading to a more efficient reaction than that under chemical redox conditions.