First pilot study of extracellular volume MRI measurement in peripheral muscle of systemic sclerosis patients suggests diffuse fibrosis.
Raluca DumitruAlex GoodallDavid BroadbentFrancesco Del GaldoAi Lyn TanJohn BiglandsMaya H BuchPublished in: Rheumatology (Oxford, England) (2021)
This hypothesis-generating study showed higher ECV in SSc patients compared to HV as well as association of ECV with suspected myopathy, suggesting the presence of diffuse fibrosis in the peripheral muscle of SSc patients. Further studies are needed to understand the nature of SSc myopathy.