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Real-world Study on the Effect of PARPi as Maintenance Therapy on Platinum Sensitivity after First- and Second-line Chemotherapy in Patients with Recurrent High-grade Serous Epithelial Ovarian Cancer.

Yanglong GuoXi ChenXuedong TangShan PanTao ZhuYingli Zhang
Published in: Current cancer drug targets (2024)
Patients with rHGSOC using a PARPi were more likely to be platinum-sensitive and develop platinum resistance independent of PARPi duration. Care should be taken when using a PARPi as maintenance therapy after first- and second-line chemotherapy.
Keyphrases
  • high grade
  • low grade
  • healthcare
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  • palliative care
  • squamous cell carcinoma
  • radiation therapy
  • mesenchymal stem cells
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