Sex differences in obesity related cancer incidence in relation to type 2 diabetes diagnosis (ZODIAC-49).
Dennis SchrijndersSteven H HendriksNanne KleefstraPauline A J VissersJeffrey A JohnsonGeertruida H de BockHenk J G BiloGijs W D LandmanPublished in: PloS one (2018)
Women with T2DM seem to have a substantially higher obesity-related cancer risk. As opposed to men, in women this risk was already increased years before diabetes diagnosis. These results could imply that a relative advantage of women in the general population with regard to cancer risk is lost in women with T2DM.
Keyphrases
- type diabetes
- glycemic control
- insulin resistance
- polycystic ovary syndrome
- weight loss
- metabolic syndrome
- cardiovascular disease
- high fat diet induced
- weight gain
- pregnancy outcomes
- papillary thyroid
- breast cancer risk
- adipose tissue
- cervical cancer screening
- skeletal muscle
- body mass index
- squamous cell carcinoma
- squamous cell