Autophagy-related biomarkers in preeclampsia: the underlying mechanism, correlation to the immune microenvironment and drug screening.

Rui WanPeng YaoYuxiu WangLele ZhangWei GuoMeiying DuYu WangWenbiao ShiWeili Li

Published in: BMC pregnancy and childbirth (2024)

PKM, LEP, and HK2 could be promising biomarkers for preeclampsia, which might regulate the pathogenesis of preeclampsia via metabolism pathways and immune microenvironment. Baicalein and luteolin could be potential therapeutics for preeclampsia.

Keyphrases

early onset
pregnancy outcomes
stem cells
cell death
small molecule
oxidative stress
signaling pathway
pregnant women
endoplasmic reticulum stress
emergency department
endothelial cells
risk assessment
high glucose