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Building bridges between cellular and molecular structural biology.

Ardan PatwardhanRobert BrandtSarah J ButcherLucy CollinsonDavid GaultKay GrünewaldCorey HeckselJuha T HuiskonenAndrii IudinMartin L JonesPaul K KorirAbraham J KosterIngvar LagerstedtCatherine L LawsonDavid MastronardeMatthew McCormickHelen ParkinsonPeter B RosenthalStephan SaalfeldHelen R SaibilSirarat SarntivijaiIrene Solanes ValeroSriram SubramaniamJason R SwedlowIlinca TudoseMartyn WinnGerard J Kleywegt
Published in: eLife (2017)
The integration of cellular and molecular structural data is key to understanding the function of macromolecular assemblies and complexes in their in vivo context. Here we report on the outcomes of a workshop that discussed how to integrate structural data from a range of public archives. The workshop identified two main priorities: the development of tools and file formats to support segmentation (that is, the decomposition of a three-dimensional volume into regions that can be associated with defined objects), and the development of tools to support the annotation of biological structures.
Keyphrases
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