TSH and FT4 Reference Intervals in Pregnancy: A Systematic Review and Individual Participant Data Meta-Analysis.
Joris A J OsingaArash DerakhshanGlenn E PalomakiGhalia AshoorTuija MännistöSpyridoula MarakaLiangmiao ChenSofie BliddalXuemian LuPeter N TaylorTanja G M VrijkotteFang-Biao TaoSuzanne J BrownFarkhanda GhafoorKris PoppeFlora VeltriLida ChatziBijay VaidyaMaarten A C BroerenBeverley M ShieldsSachiko ItohLorena MossoPolina V PopovaAnna D AnopovaReiko KishiAshraf AminorroayaMaryam KianpourAbel López-BermejoEmily OkenAmna PirzadaMarina VafeiadiWichor M BramerEila SuvantoJun YoshinagaKun HuangJudit BassolsLaura BoucaiUlla Feldt-RasmussenElena N GrinevaElizabeth N PearceErik K AlexanderVictor J M PopScott McGill NelsonJohn P WalshRobin P PeetersLayal ChakerKypros H NicolaidesMary E D'AltonTim I M KorevaarPublished in: The Journal of clinical endocrinology and metabolism (2022)
We provide an overview of clinically relevant reference intervals for TSH and FT4 in pregnancy. The results of the meta-analysis indicate that future studies can adopt a simplified study setup without additional exclusion criteria.