Periductal bile acid exposure causes cholangiocyte injury and fibrosis.
Miri DotanSophia FriedAdi Har-ZahavRaanan ShamirRebecca G WellsOrith Waisbourd-ZinmanPublished in: PloS one (2022)
Bile acid leakage into the submucosa after initial cholangiocyte injury may serve as a possible mechanism of disease propagation and progressive fibrosis in cholangiopathies.
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