Xanthohumol Requires the Intestinal Microbiota to Improve Glucose Metabolism in Diet-Induced Obese Mice.
Isabelle E LoganNatalia ShulzhenkoThomas J SharptonGerd BobeKitty LiuStephanie NussMegan L JonesCristobal L MirandaStephany Vasquez-PerezJamie M PenningtonScott W LeonardJaewoo ChoiWenbin WuManoj GurungJoyce P KimMalcolm B LowryAndrey MorgunClaudia S MaierJan F StevensAdrian F GombartPublished in: Molecular nutrition & food research (2021)
XN requires the intestinal microbiota to mediate its benefits, which involves complex diet-host-microbiota interactions with changes in both microbial composition and functional capacity. The study results warrant future metagenomic studies which will provide insight into complex microbe-microbe interactions and diet-host-microbiota interactions.