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Tracer uptake in mediastinal and paraaortal thoracic lymph nodes as a potential pitfall in image interpretation of PSMA ligand PET/CT.

Ali Afshar OmeriehLars Peter SattlerKatja SteigerTim Holland-LetzMarcelo Livorsi da CunhaWalter MierOliver NeelsKlaus KopkaWilko WeichertUwe Haberkorn
Published in: European journal of nuclear medicine and molecular imaging (2018)
PSMA-positive mediastinal/paraaortal benign LN were visible in a notable proportion of patients. PSMA-positivity on the histopathological level was associated with the activation state of the LN. However, in contrast to LN metastases of PC, they presented with significantly lower uptake, which, in addition, usually decreased over time.
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