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Impact of intestinal dysbiosis-related drugs on the efficacy of immune checkpoint inhibitors in clinical practice.

Elisabeth Perez-RuizJ Jiménez-CastroM-A Berciano-GuerreroJ ValdiviaS Estalella-MendozaF ToscanoM Rodriguez de la Borbolla ArtachoM Garrido-SilesM J Martínez-BautistaR Villatoro RoldanF Rivas-RuizE Nogales-FernándezC MoralesB Pérez-ValderramaL De la Cruz-MerinoA Rueda
Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2020)
Response to ICIs may be influenced by the use of drugs that lead to intestinal dysbiosis. Although a confirmatory prospective controlled study is required, our findings should be taken into account when analyzing ICI efficacy.
Keyphrases
  • clinical practice
  • drug induced