Pretreatment 18F-FDG PET/CT combined with quantification of clonal circulating plasma cells as a potential risk model in patients with newly diagnosed multiple myeloma.

Yoshiaki AbeKentaro NaritaHiroki KobayashiAkihiro KitadateDaisuke MiuraMasami TakeuchiEri O'uchiToshihiro O'uchiKosei Matsue

Published in: European journal of nuclear medicine and molecular imaging (2019)

The PET-CPC staging system predicted survival outcomes independently of established risk factors in patients with newly diagnosed MM. Pretreatment 18F-FDG PET/CT assessment combined with CPC quantification may improve the prognostication of MM and facilitate the development of novel risk-adapted approaches for MM.

Keyphrases

newly diagnosed
risk factors
multiple myeloma
induced apoptosis
pet ct
computed tomography
lymph node
cell cycle arrest
risk assessment
cell proliferation
signaling pathway
pet imaging
breast cancer risk