Nanopore 16S sequencing enhances the detection of bacterial meningitis after neurosurgery.

Yoonhyuk JangSeondeuk KimNarae KimHyoshin SonEun Jin HaEun Jung KohJi Hoon PhiChul-Kee ParkJeong Eun KimSeung-Ki KimSang Kun LeeWon-Sang ChoJangsup Moon Kon Chu

Published in: Annals of clinical and translational neurology (2022)

CSF nanopore 16S sequencing was more effective than conventional CSF culture studies in postoperative bacterial meningitis and may contribute to evidence-based decisions for antibiotic maintenance and discontinuation.

Keyphrases

cerebrospinal fluid
single molecule
single cell
patients undergoing
solid state
loop mediated isothermal amplification
label free
real time pcr
case control