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New drug candidates for treatment of atypical meningiomas: An integrated approach using gene expression signatures for drug repurposing.

Zsolt ZadorAndrew T KingNophar Geifman
Published in: PloS one (2018)
To our knowledge this is the first study which combines relatively new, yet established computational techniques to identify additional treatments for a difficult to manage cerebral neoplasm. Beyond proposing already approved drug candidates in the management of atypical meningioma the study highlights the promise held by computational techniques in improving our management strategies.
Keyphrases
  • gene expression
  • healthcare
  • dna methylation
  • emergency department
  • subarachnoid hemorrhage
  • low grade
  • artificial intelligence
  • brain injury
  • electronic health record
  • smoking cessation
  • optic nerve