Immune Response to LinB13, a Lutzomyia Intermedia Salivary Protein Correlates With Disease Severity in Tegumentary Leishmaniasis.
Augusto M CarvalhoSayonara M VianaBruno B AndradeFabiano OliveiraJesus G ValenzuelaEdgar M CarvalhoCamila I de OliveiraPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
In this study, we observed an association between humoral and cellular immune response to the sand fly salivary protein rLinB-13 and disease severity in tegumentary leishmaniasis. This study brings evidence that immunity to rLinB-13 influences disease outcome in L. braziliensis infection and results indicate that positive serology to rLinB-13 IgG can be used as a marker of DL, an emerging and severe form of disease caused by L. braziliensis.
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