Genetic determinants of acute asthma therapy response in children with moderate-to-severe asthma exacerbations.

Sze Man TseMaja KrajinovicBhupendrasinh F ChauhanRoger ZemekJocelyn GravelDominic ChalutNaveen PoonaiCaroline QuachSophie LabergeFrancine M Ducharmenull null

Published in: Pediatric pulmonology (2019)

Three SNPs were significantly associated with ED management failure in addition to clinical predictors, contributing to inter-individual variability. None has been previously associated with treatment response to acute asthma management.

Keyphrases

chronic obstructive pulmonary disease
liver failure
respiratory failure
lung function
genome wide
emergency department
aortic dissection
cystic fibrosis
young adults
allergic rhinitis
high intensity
gene expression
intensive care unit
mesenchymal stem cells
bone marrow