Inhibitory effects of Sanguisorba officinalis root extract on HYBID (KIAA1199)-mediated hyaluronan degradation and skin wrinkling.
Hiroyuki YoshidaK YamazakiA KomiyaM AokiS KasamatsuT MurataT SayoM Z CilekY OkadaY TakahashiPublished in: International journal of cosmetic science (2019)
Sanguisorba officinalis root extract showed an anti-HYBID-mediated HA degradation activity and anti-wrinkle activity on human facial skin, which is accompanied by the improvement in elasticity. Our study provides the possibility of a new strategy to inhibit HYBID-mediated HA degradation for anti-wrinkle care.