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A Pilot Study of Neoadjuvant Nivolumab, Ipilimumab, and Intralesional Oncolytic Virotherapy for HER2-negative Breast Cancer.

Vina P NguyenKatie M CampbellTheodore Scott NowickiNila ElumalaiEgmidio MedinaIgnacio Baselga CarreteroMaggie L DiNomeHelena R ChangDenise K OsegueraAntoni RibasJohn A Glaspy
Published in: Cancer research communications (2023)
Systemic immune checkpoint blockade with a programmed death receptor 1 and a CTL antigen-4 blocking antibody, combined with intralesional oncolytic virotherapy, is a chemotherapy-free combination aimed at inducing an antitumor immune response locally and systemic immunity.
Keyphrases
  • immune response
  • locally advanced
  • rectal cancer
  • lymph node
  • squamous cell carcinoma
  • dendritic cells
  • binding protein
  • young adults