Clonal cytopenia of undetermined significance (CCUS) with dysplasia is enriched for MDS-type molecular findings compared to CCUS without dysplasia.
Audrey N JajoskyNavid SadriHoward J MeyersonKwadwo A OduroAshwin KelkarBrynn FitzgeraldBenjamin K TomlinsonErika M MooreRose C BeckPublished in: European journal of haematology (2021)
CCUS-D patients exhibit a molecular (but not clinical) profile more similar to MDS patients than CCUS-ND, suggesting CCUS-D may represent a more immediate precursor to MDS and may warrant closer clinical follow-up.