Targeting epigenetic mechanisms for chronic visceral pain: A valid approach for the development of novel therapeutics.
Tijs LouwiesCasey O LigonAnthony C JohnsonBeverley Greenwood-Van MeerveldPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2018)
The goal of this review is to highlight the latest discoveries made toward understanding the epigenetic mechanisms that are involved in the development or maintenance of chronic visceral pain. Furthermore, this review will provide evidence supporting that targeting these epigenetic mechanisms may represent a novel approach to treat chronic visceral pain.