Multiparametric imaging hippocampal neurodegeneration and functional connectivity with simultaneous PET/MRI in Alzheimer's disease.

Shaozhen YanChaojie ZhengBixiao CuiZhigang QiZhilian ZhaoYanhong AnLiyan QiaoYing HanYun ZhouJie Lu

Published in: European journal of nuclear medicine and molecular imaging (2020)

Our findings demonstrate that the associations existed at subregional hippocampal level between the functional connectivity measured by fMRI and neurodegeneration measured by structural MRI and 18F-FDG PET. Our results may provide a basis for precision neuroimaging of hippocampus in AD.

Keyphrases

functional connectivity
resting state
pet ct
positron emission tomography
pet imaging
contrast enhanced
computed tomography
cerebral ischemia
magnetic resonance imaging
diffusion weighted imaging
high resolution
magnetic resonance
blood brain barrier
prefrontal cortex
mass spectrometry
cognitive impairment