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Methods to Quantify the Importance of Parameters for Model Updating and Distributional Adaptation.

David GlynnSusan GriffinNils GutackerSimon M Walker
Published in: Medical decision making : an international journal of the Society for Medical Decision Making (2024)
It can require considerable analyst time to search for evidence to update a model or to adapt a model to take account of equity concerns.In this article, we provide a quantitative method to prioritze parameters to 1) update existing models to reflect potential new evidence and 2) adapt existing models to estimate distributional outcomes.We define metrics that quantify the extent to which the parameters in a model have been updated or adapted.We provide R code that can quickly rank parameter importance and calculate quality metrics using only the results of a standard probabilistic sensitivity analysis.
Keyphrases
  • type diabetes
  • adipose tissue
  • public health
  • high resolution
  • skeletal muscle
  • insulin resistance
  • quality improvement
  • mass spectrometry
  • human health