Clinical Application of Next-Generation Sequencing of Plasma Cell-Free DNA for Genotyping Untreated Advanced Non-Small Cell Lung Cancer.
Maria Gabriela O FernandesNatália Cruz MartinsConceição Souto MouraSusana GuimarãesJoana Pereira ReisAna JustinoMaria João PinaAdriana MagalhãesHenrique QueirogaJosé Carlos MachadoVenceslau HespanholJosé Luís CostaPublished in: Cancers (2021)
This study highlights the potential use of ctDNA for mutation detection in newly diagnosed NSCLC patients due to its high accuracy and correlation with clinical outcomes.
Keyphrases
- newly diagnosed
- advanced non small cell lung cancer
- end stage renal disease
- epidermal growth factor receptor
- ejection fraction
- chronic kidney disease
- small cell lung cancer
- prognostic factors
- copy number
- peritoneal dialysis
- circulating tumor
- gene expression
- patient reported outcomes
- tyrosine kinase
- label free
- climate change